Background: When adolescent boys experience close, secure relationships with their parents and peers, the implications are potentially far reaching, including lower levels of mental health problems in adolescence and young adulthood. Here we use rare prospective intergenerational data to extend our understanding of the impact of adolescent attachments on subsequent postpartum mental health problems in early fatherhood.Methods: At age 17–18 years, we used an abbreviated Inventory of Parent and Peer Attachment to assess trust, communication, and alienation reported by 270 male (...) participants in their relationships with mothers, fathers, and peers. More than a decade later, we assessed the adult males, now fathers, at 12 months postpartum for symptoms of depression, anxiety, and stress. Logistic regression was used to examine the extent to which attachment dimensions predicted paternal postpartum mental health, adjusting for potential confounding, and with assessment for interactions between parent and peer attachments.Results: Trust in mothers and peers, and good communication with fathers during adolescence, were associated with 5 to 7 percentage point reductions in postpartum mental health symptoms in early fatherhood. Weak evidence of parent-peer interactions suggested secure attachments with either parent or peer may compensate for an insecure attachment with the other.Conclusions: Our results suggest that fostering trust and communication in relationships that adolescent boys have with parents and peers may have substantial effects on rates of paternal postpartum mental health problems. The protective benefits may be preventative in intergenerational cycles of risk for mental health problems. (shrink)

In July 2020, the H3Africa Ethics and Community Engagement (E&CE) Working Group organised a webinar with ethics committee members and biomedical researchers from various African institutions throughout the Continent to discuss the issue of whether and how biological samples for scientific research may be accessed by commercial entities when broad consents obtained for the samples are silent. 128 people including Research Ethics Committee members (10), H3Africa researchers (46) including members of the E&CE working group, biomedical researchers not associated with H3Africa (...) (27), representatives from the National Institutes of Health (16) and 10 other participants attended the webinar and shared their views. Several major themes emerged during the webinar, with the topics of broad versus explicit informed consent, defining commercial use, legacy samples and benefit sharing prevailing in the discussion. This report describes the consensus concerns and recommendations raised during the meeting and will be informative for future research on ethical considerations for genomic research in the African research context. (shrink)

Long-standing theoretical education frameworks and methodologies have failed to provide space for the role mental health can play in mediating educational consequences. To illustrate the need for such space, Ebony McGee and David Stovall highlight the voices of black undergraduates they have served in the capacities of teacher, researcher, and mentor. Building from the theoretical contributions of intellectual giants like Frantz Fanon and W. E. B. Du Bois, the authors attempt to connect oppressive social systems to the psyche of (...) the oppressed in a way that is relevant to black students. McGee and Stovall pose a challenge to the current research trend of attributing the survival of black students at traditionally white institutions primarily to grit, perseverance, and mental toughness, noting that research on the aforementioned qualities often fails to properly acknowledge multiple forms of suffering. Utilizing the lens of Critical Race Theory, the authors also challenge the construct of grit to consider the extent to which the mental health concerns of black students go undetected. Although critical race theorists have unmasked and attacked the racial trauma experienced at all levels of the educational system, the connection of CRT to mental health and wellness research is in its embryonic stages. For these reasons, McGee and Stovall argue that CRT scholars need to incorporate praxis to address mental health and wellness in order to address a fuller spectrum of black students' racialized worlds. Ultimately, they seek interdisciplinary perspectives that can help identify and foster strategies to support black students in the project and process of healing from multiple forms of racialized trauma they experience within and beyond their educational encounters. (shrink)

When recalling autobiographical events, people not only retrieve event details but also the feelings they experienced. The current study examined whether people are able to consistently recall the intensity of past feelings associated with two consequential and negatively valenced events, i.e. the 9/11 attack (N = 769) and the COVID-19 pandemic (N = 726). By comparing experienced and recalled intensities of negative feelings, we discovered that people systematically recall a higher intensity of negative feelings than initially reported – overestimating the (...) intensity of past negative emotional experiences. The COVID-19 dataset also revealed that individuals who experienced greater improvement in emotional well-being displayed smaller biases in recalling their feelings. Across both datasets, the intensity of remembered feelings was correlated with initial feelings and current feelings, but the impact of the current feelings was stronger in the COVID-19 dataset than in the 9/11 dataset. Our results demonstrate that when recalling negative autobiographical events, people tend to overestimate the intensity of prior negative emotional experiences with their degree of bias influenced by current feelings and well-being. (shrink)

Aggleton & Brown argue that a hippocampal-anterior thalamic system supports the “recollection” of contextual information about previous events, and that a separate perirhinal-medial dorsal thalamic system supports detection of stimulus “familiarity.” Although there is a growing body of human literature that is in agreement with these claims, when recollection and familiarity have been examined in amnesics using the process dissociation or the remember/know procedures, the results do not seem to provide consistent support. We reexamine these studies and describe the results (...) of an additional experiment using a receiver operating characteristic (ROC) technique. The results of the reanalysis and the ROC experiment are consistent with Aggleton & Brown's proposal. Patients with damage to both regions exhibit severe deficits in recollection and smaller, but consistent, deficits in familiarity. (shrink)

This article reviews the strengths and limitations of five major paradigms of medical computer-assisted decision making (CADM): (1) clinical algorithms, (2) statistical analysis of collections of patient data, (3) mathematical models of physical processes, (4) decision analysis, and (5) symbolic reasoning or artificial intelligence (Al). No one technique is best for all applications, and there is recent promising work which combines two or more established techniques. We emphasize both the inherent power of symbolic reasoning and the promise of artificial intelligence (...) and the other techniques to complement each other. (shrink)

Giardia lamblia, a protozoan parasite that causes widespread diarrheal disease, expresses a surface membrane associated lectin, taglin, which is specifically activated by limited proteolysis with trypsin, a protease that is present in abundance at the site of infection. When activated, taglin agglutinates enterocytes which are the cells to which the parasite adheres in vivo, and in addition, binds to isolated brush border membranes of these cells. These findings suggest that this lectin may be involved in the host‐parasite interaction. Taglin is (...) most specific for terminal phosphomannosyl residues and its binding to red cells is mediated by cell surface phosphate residues. Hemagglutinating activity induced by taglin is most active at pH6.5 and is dependent on divalent cations. A monoclonal antibody to taglin reacts with the surface membrane of live trophozoites and recognizes a protein of 28/30 kDa in lysates of Giardia trophozoites, by immunoblotting. This finding is confirmed by direct demonstration of lectin activity by erythrocyte binding to proteins electroblotted to nitrocellulose, which revealed specific red cell binding to giardial protein bands in the same molecular weight range as those recognized by the monoclonal antibody. (shrink)

In perception science, an alternative to focusing on individual sensory systems is to describe the environment to be perceived. We focus on the emergent dynamics of human-environment interactions as an important category of the environment to be perceived. We argue that information about such dynamics is available in subtle patterns of movement variability that, of necessity, stimulate multiple sensory systems.

"Of all the economic bubbles that have been pricked," the editors of The Economist recently observed, "few have burst more spectacularly than the reputation of economics itself." Indeed, the financial crisis that crested in 2008 destroyed the credibility of the economic thinking that had guided policymakers for a generation. But what will take its place? In How the Economy Works, one of our leading economists provides a jargon-free exploration of the current crisis, offering a powerful argument for how economics must (...) change to get us out of it. Roger E. A. Farmer traces the swings between classical and Keynesian economics since the early twentieth century, gracefully explaining the elements of both theories. During the Great Depression, Keynes challenged the longstanding idea that an economy was a self-correcting mechanism; but his school gave way to a resurgence of classical economics in the 1970s-a rise that ended with the current crisis. Rather than simply allowing the pendulum to swing back, Farmer writes, we must synthesize the two. From classical economics, he takes the idea that a sound theory must explain how individuals behave-how our collective choices shape the economy. From Keynesian economics, he adopts the principle that markets do not always work well, that capitalism needs some guidance. The goal, he writes, is to correct the excesses of a free-market economy without stifling entrepreneurship and instituting central planning.Recent events have shown that we cannot afford to treat economics as an ivory-tower abstraction. It has a direct impact on our lives by guiding regulators and policymakers as they make decisions with far-reaching practical consequences. Written in clear, accessible language, How the Economy Works makes an argument that no one should ignore. (shrink)

В первую книгу сборника включены исследования и материалы, посвященные творчеству Сергея Николаевича Дурылина - писателя, поэта, философа и богослова, и творчеству представителей русского культурного ренессанса первой трети XX века.

I would like to stress Vadim Mikhailovich's [Mezhuev's] position and clarify our conversation about culturology. It is constantly repeated that culturology is a science. It is my profound conviction that culturology is not a science. Culturology is a distinctive phenomenon of Russian culture and represents a certain intellectual movement. If one briefly surveys the history of its emergence, its philosophical origin becomes obvious. This intellectual movement consists of three levels, if one takes into account the "-logy" ending. First, the philosophical (...) level, from which in the 1970s culture began to be conceived as a special field of knowledge in our country. Then, humanistic knowledge: a great many representatives of the humanities in Russia-historians, art specialists, art critics, essayists-studied culture. Finally, there is the socioscientific tendency, which is just beginning to form in Russia and carries the internationally accepted name of social and cultural anthropology. All of us are synergistically attracted to these three tendencies, which comprise what is called culturology. The question of how these three tendencies of knowledge are correlated in the framework of the given intellectual movement is, in my view, extremely important. For quite some time now, there has been no reflection in Russia on the foundations of scientific and philosophical knowledge, but such reflection is necessary. To advance along the road of rational knowledge it is important to reflect in what cognitive space we find ourselves, what we are doing within its boundaries, and for what reason. From this point of view, neither philosophers nor representatives of the humanities or the social sciences will renounce their positions of observer. Moreover, I agree with Mezhuev that there is no single philosophy, humanistic conception, or theory of culture. Anyone who is engaged professionally in the study of cultural phenomena can choose his initial foundations. As Vadim Mezhuev correctly notes, the significance of philosophy for other types of knowledge lies in the fact that there are borderline areas of man's existence in the world. However, they are identified in different ways by different philosophies: positivism, phenomenology, classical Platonism, Aristotelianism, Kantianism, and so forth. Representatives of humanistic and socioscientific knowledge are free to choose any metaphysics. Philosophers will continue to attend to their business in their subject area, and scientists in theirs. But it is important periodically to determine rationally when there must be close and complementary relations between the three components of this intellectual movement and when they must exist in parallel. Then questions such as who has priority and who is the guardian of truth will not arise. If the tendencies have diverged in parallel, then the representatives of each of them are occupied within their domains with questions which are irrelevant in other fields of knowledge or for other theoretical models. At the end of the twentieth century, to pose the question of scientism or antiscientism is senseless because today we know that there are different forms of rationality and that science is not the only, and is quite a narrow, form of rationality. Myth too is rational. It is expressed in categories and has a particular inner logic. We recognize myth as a rational cultural entity, because it is represented in symbolic form as an ordered sequence of judgments, as an artifact. But it differs from scientific theory. That is why it is fruitful to reflect on what forms of rationality are relevant to what levels of knowledge. I agree with Ogurtsov, who says that these forms penetrate in one way or another into every culturally institutionalized form of knowledge. Indeed, in philosophical knowledge there are elements of everyday, mythological, and scientific knowledge, but this does not negate the distinctive nature of the philosophical form of knowledge. In science there are elements of metaphysics, mythology, and everyday knowledge, but this does not cancel the particularities of the scientific form of knowledge. The same is true of the humanistic form, which is in principle irremovable from the framework of institutionalized knowledge, at least for now. I do not agree with Ogurtsov that I give the humanistic form of knowledge a negative evaluation. Humanistic knowledge begins to be significant in a period of a cognitive paradigm shift. This, we can say, is apparent today, at a time of transition from the grand style of modernism in its postmodern mode to the building of the foundations for a new whole. The point is that the humanistic form of knowledge enables us to isolate at the outset those areas of the unknown at which we arrive because of the limitations inherent in other forms of rationality. It is closest to everyday and empirical categories of knowledge and forms of ideas; hence, particularism, image syncretism, and mobility are its distinctive features. But without this humanistic level no further step is possible in either scientific or philosophical knowledge. The breakdown into these forms of knowledge- philosophical, humanistic, and scientific-may be primitive, but we have to start our reflection on the foundations of our cognitive relationship to our surroundings somewhere. The identification of the forms of knowledge makes it possible to draw the conclusion that, unlike philosophical and humanistic knowledge, socioscientific knowledge is modeled on the natural sciences. From this it becomes obvious that the distinctive features of the object of social sciences determine also the special nature of the categorial apparatus, operationalization, selection method, and information analysis. I do not insist that the model I suggest must be accepted. Other models can be constructed. But let us start with a simpler comparison of types of knowledge and later we shall differentiate them. I started from this level because in our culture such a division is apparent and generally accepted. There are the philosophical, humanistic, and scientific forms of knowledge. They are irreducible to one another, they perform entirely different functions in the knowledge of man's relationship to the environment, and express different views about how man lives in culture. I agree that philosophy is exactly existence in culture with a singling out of the limits of this existence. But representatives of humanistic and socioscientific knowledge also deal with existence in culture. What is important for the philosopher is the direction of knowledge from within to the outside; for the representative of humanistic knowledge it is the description of how he exists among a multitude of seemingly diverse and divergent artifacts and processes; and for the scientist it is the order of the philosophically and humanistically defined reality in order to control it the better. (shrink)

В настоящей монографии проведено исследование современного техногенного развития социум и природы и их трансформации под воздействием достижений научно-технического прогресса и разрастания искусственной среды обитания человечества.